Inflammation

Ferritin (Iron Stores)

Ferritin is a protein that stores iron and releases it in a controlled fashion. Blood ferritin levels are the most reliable indicator of total body iron stores. Ferritin also acts as an acute-phase reactant, meaning levels can rise during inflammation, infection, or liver disease — making interpretation context-dependent.

Optimal Ranges

Clinical (NHS) Range

30-400 ng/mL

ng/mL

Performance-Optimised Range

80-150 ng/mL

ng/mL

The clinical range defines what is considered medically “normal” — broad enough to cover 95% of the population. The performance range reflects where research and clinical experience suggest most people feel and function at their best.

Why It Matters

Why Ferritin matters for performance

Iron is essential for oxygen transport, energy production, and cognitive function. Low ferritin — even within the 'normal' clinical range — is one of the most underdiagnosed causes of persistent fatigue in active men. Athletes and men who train regularly deplete iron through sweat, foot-strike haemolysis, and increased red blood cell turnover. Ferritin below 50 ng/mL in an active man often correlates with reduced endurance, poor recovery, and unexplained performance plateaus.

Symptoms

Signs your levels may be off

Low / Deficiency

  • Persistent fatigue despite adequate sleep
  • Breathlessness during training
  • Pale skin and dark circles
  • Restless legs
  • Cold hands and feet
  • Reduced training capacity

High / Excess

  • Joint pain
  • Abdominal pain
  • Skin bronzing
  • Liver damage (haemochromatosis)

Dietary Sources

Foods that support Ferritin levels

Red meat (beef, lamb)Liver and organ meatsDark poultry meatLentils and chickpeasSpinach and dark leafy greensFortified cereals

Supplementation

Evidence-based supplementation approach

Iron bisglycinate is the preferred supplemental form due to superior absorption and fewer gastrointestinal side effects. Typical dose: 25-50 mg elemental iron daily, taken with vitamin C (200 mg) to enhance absorption. Avoid taking with calcium, tea, or coffee which inhibit absorption. Iron supplementation should only be initiated when ferritin is confirmed low — excess iron is toxic. Retest at 90 days.

Research

Key study

Iron deficiency without anaemia is a potential cause of fatigue: meta-analyses of randomised controlled trials and observational studies

Houston BL, Hurrie D, Graham J, et al.

BMJ Open (2018)

DOI: 10.1136/bmjopen-2018-022199

Related Biomarkers

Related Guides

Test your Ferritin levels

Ferritin is included in the Helvy 50+ biomarker panel. Get your results in 5 days with a personalised protocol.

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This content is for educational purposes only and does not constitute medical advice. Your data suggests areas for optimisation, but any concerns should be discussed with a qualified healthcare professional. If your results flag values outside safe ranges, we recommend consulting your GP.