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Vitamins & Minerals
In the UK, the standard clinical (NHS) reference range for Iron (Serum Iron, TIBC & Transferrin Saturation) is 10-30 µmol/L (serum iron), with 15-25 µmol/L (serum iron), 20-45% transferrin sat. considered the performance-optimised range. A result within these ranges suggests typical status; only a qualified clinician can interpret an individual reading.
Iron is an essential mineral that carries oxygen in your blood, supports energy production in every cell, and plays a key role in immune function and cognitive performance. A full iron panel — serum iron, total iron-binding capacity (TIBC), and transferrin saturation — gives a far more complete picture than ferritin alone. Together, these markers reveal whether your body is absorbing, transporting, and utilising iron effectively.
Optimal range · UK
15-25 µmol/L (serum iron), 20-45% transferrin sat.
Performance-optimised band · clinical (NHS) range 10-30 µmol/L (serum iron)
Reference ranges for Iron, not a personal result. Any individual reading should be interpreted by a qualified clinician.
Optimal ranges
| Range | Value |
|---|---|
| Clinical (NHS) reference range | 10-30 µmol/L (serum iron) |
| Performance-optimised range | 15-25 µmol/L (serum iron), 20-45% transferrin sat. |
The clinical range defines what is considered medically “normal” — broad enough to cover 95% of the population. The performance range reflects where research and clinical experience suggest most people feel and function at their best. A result in either range suggests typical status and is not a diagnosis; any individual reading should be interpreted by a qualified clinician.
Why it matters
Iron deficiency is the most common nutritional deficiency in the UK, affecting an estimated 3% of men and up to 25% of women of reproductive age according to the NHS. For active people, iron demands are significantly higher — endurance training, heavy sweating, and even foot-strike haemolysis from running can deplete iron stores faster than diet replaces them. Low iron doesn't just mean anaemia: even subclinical deficiency impairs oxygen delivery to muscles, slows recovery, and causes persistent fatigue and brain fog that many people attribute to stress or poor sleep. A full iron panel catches problems that a standalone ferritin test can miss, such as iron-loading disorders or poor absorption despite adequate intake.
Symptoms
Low / Deficiency
High / Excess
Dietary sources
Supplementation
Iron bisglycinate is the gold standard supplemental form — absorbed 2-4x better than ferrous sulphate with far fewer gut side effects. Typical dose: 15-25 mg elemental iron daily when deficiency is confirmed by blood testing. Always take with 200 mg vitamin C (or alongside vitamin C-rich foods like citrus or peppers) to boost absorption by up to 67%. Avoid taking iron within 2 hours of calcium supplements, tea, coffee, or dairy, as these inhibit absorption. Never supplement iron without testing first — excess iron is toxic and cannot be easily excreted. The hereditary condition haemochromatosis (affecting ~1 in 200 people of Northern European descent) causes dangerous iron overload. Retest after 90 days to confirm response and adjust dosing.
Testing
Iron is measured from a blood sample. With Helvy, that means a finger-prick kit taken at home and posted to a UKAS-accredited UK laboratory, with results in around 5 days, reviewed by a qualified clinician. Your result is reported against both the clinical range (10-30 µmol/L (serum iron)) and the performance-optimal range (15-25 µmol/L (serum iron), 20-45% transferrin sat.), so you can see not just whether you are “normal” but whether you are optimal. If you make a change, retest after 8-12 weeks to confirm it worked.
Research
Iron deficiency anaemia: assessment, prevention and control — a guide for programme managers
World Health Organization
WHO Technical Report Series (2001)
DOI: 10.1016/S0140-6736(15)60865-0Related biomarkers
Related guides
This content is for educational purposes only and does not constitute medical advice. Your data suggests areas for optimisation, but any concerns should be discussed with a qualified healthcare professional. If your results flag values outside safe ranges, we recommend consulting your GP.
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